CometAssay LMAgarose from R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

(2) Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium bindingThe Journal of biological chemistryAugust 1, 2023Shimizu N, Hamada Y, Morozumi R, Yamamoto J, Iwai S, Sugiyama KI, Ide H, Tsuda M.5.0 × 104 cells were washed in prechilled PBS and mixed with 45 μl aliquots of CometAssay LMAgarose (4250-050-02, R&D Systems) at 37 °C. Cell suspensions were immediately transferred onto a CometSlide slide (4250-200-03,

(4) Protein adduction causes non-mutational inhibition of p53 tumor suppressorCell reportsJanuary 31, 2023Caspa Gokulan R, Paulrasu K, Azfar J, El-Rifai W, Que J, Boutaud OG, Ban Y, Gao Z, Buitrago MG, Dikalov SI, et al.

(5) Co-inhibition of ATM and ROCK synergistically improves cell proliferation in replicative senescence by activating FOXM1 and E2F1Communications BiologyDecember 1, 2022Eun Jae Yang et al.in 0.5 ml of ice-cold PBS. The cell suspension (10 μl) was blended with 100 μl of warmed LMAgarose (4250-050-02; R&D Systems), and the mixture (50 μl) was then swiftly spread on slides as evenly as possible. DNA

(6) Impacts of arsenic on Rad18 and translesion synthesisToxicology and applied pharmacologyNovember 1, 2022Volk LB, Cooper KL, Jiang T, Paffett ML, Hudson LG.

(7) The N(6)-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrityNature communicationsOctober 28, 2022Yoshinaga M, Han K, Morgens DW, Horii T, Kobayashi R, Tsuruyama T, Hia F, Yasukura S, Kajiya A, Cai T, et al.

(8) Targeting DNA Repair with Combined Inhibition of NHEJ and MMEJ Induces Synthetic Lethality in TP53-Mutant CancersCancer researchOctober 17, 2022Patterson-Fortin J, Bose A, Tsai WC, Grochala C, Nguyen H, Zhou J, Parmar K, Lazaro JB, Liu J, McQueen K, et al.

(12) Combination treatment of arsenic trioxide and osimertinib in recurrent and metastatic head and neck squamous cell carcinomaAmerican journal of cancer researchJanuary 1, 2022Hsieh CY, Chang WC, Lin CC, Chen JH, Lin CY, Liu CH, Lin C, Hung MC.

(13) Genetic vulnerabilities upon inhibition of DNA damage responseNucleic acids researchAugust 20, 2021Wang C, Tang M, Chen Z, Nie L, Li S, Xiong Y, Szymonowicz KA, Park JM, Zhang H, Feng X, et al.

(15) The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repairCell reportsJune 29, 2021Luessing J, Sakhteh M, Sarai N, Frizzell L, Tsanov N, Ramberg KO, Maretto S, Crowley PB, Lowndes NF.

(16) DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylationNature communicationsMay 3, 2021Ren W, Fan H, Grimm SA, Kim JJ, Li L, Guo Y, Petell CJ, Tan XF, Zhang ZM, Coan JP, et al.

(18) Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR inhibitorsTheranosticsJanuary 1, 2021Grimley E, Cole AJ, Luong TT, McGonigal SC, Sinno S, Yang D, Bernstein KA, Buckanovich RJ.

(20) Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcriptionNucleic acids researchJuly 26, 2019Velichko AK, Petrova NV, Luzhin AV, Strelkova OS, Ovsyannikova N, Kireev II, Petrova NV, Razin SV, Kantidze OL.

Citations (26)